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![]() And it also depends on what your goals are of course. So never give up and never let it keep you from starting. If you have friends or relatives who are into music then you can also share your work with others and get feedback.įirst of all, I want to tell you that anybody can learn it. ![]() To start your composition projects you can use software like Musescore, to write them down and organize them. Of course, the best way to improve your skills and train your creativity is to practice composing your own music regularly. As your instructor in our classes, I give composition assignments that meet the interests of any student. So for example what elements they use, how they structure their pieces, and what emotions they convey. By listening to and analysing their music you can study how other composers created their music. You can find a great list of books on my website.Īnother great way to learn musical composition is to listen to and analyze music from different composers, genres, and periods. But you can also read books or articles on music theory, harmony, melody, rhythm, form, and orchestration. You can take an extra online music composition course from platforms like Udemy or Coursera. I will give you all the composition tools that you need for expressing yourself in music.įor any beginning composition student, there are many different ways to learn to start writing. I will teach you how to write music in any program that you like. You will develop your own musical style and become better with each composition that you write. I will teach and show you all the steps of composing music. What are music composition classes? What do you learn in a music composition class? The easy thing? You don’t have to search for ‘music composition classes near me’. So why not learn music composition from home? After all, this is the place where you feel most comfortable and secure. ![]() But thanks to the internet music education is not fixed to your location anymore. You can teach yourself music composition, but it is tough because you have nobody to help you when you are stuck. Compose something small every (second) day.Find out what you like and try it yourself.Listen to a lot of music and analyse it.Here is how you can learn music composition and write new music. This is composing your own songs and music. You love to create music and now you want to take your creativity to the next step. ![]() Pratt’s always got something big going on, and his post-dino career has been no exception: In addition to voicing Mario and reprising his Star-Lord role for the third and final Guardians movie (both in 2023), Pratt is set to purr it up in 2024 as the voice of a certain comic-strip famous, lasagna-loving feline in The Garfield Movie, as well as delve back into sci-fi with the The Electric State - a movie that’ll reunite him with MCU directing veterans the Russo brothers and Captain America heir Anthony Mackie. Movie (streaming here on Peacock!), it’s hard to yank your eyes (and ears) away from Pratt, a natural-born comedian who cut his early funny chops as part of the hilarious sitcom cast of Parks and Recreation (also streaming on Peacock here). ![]() ![]() Whether he’s playing Guardians of the Galaxy goofball Peter Quill in the MCU or bringing a buoyant bounce to Nintendo’s mustachioed mascot in The Super Mario Bros. Jurassic World Official Trailer #1 (2015) - Chris Pratt, Jake Johnson Movie HD/Rotten Tomatoes Trailers YouTube Dimitrios Kambouris/Getty Imagesĭid ya know? Chris Pratt’s role of chief Raptor whisperer Owen Grady in all three Jurassic World movies was originally meant for fellow Marvel movie alum Josh Brolin - a Jurassic casting switch that’s hard to envision in hindsight. Tag along, if you dare, as we take a scaly step back in time to Isla Nublar - all to gather some up-to-date intel on our favorite Jurassic World stars.Ĭhris Pratt appears as Owen Grady in Jurassic World (2015) Chris Pratt attends the Panerai Store Opening on Jin New York City. RELATED: Jurassic Park Still Knows How to Make Bank at the Box Office, Even 30 Years Later But what’s the story on the rest of the movie’s sizable cast - and what are supporting Jurassic World stars like Vincent D’Onofrio, Jake Johnson, and Judy Greer up to today? The Jurassic World trilogy captured many of its biggest starring names smack in the middle of already-stellar A-list careers, a screen phenomenon still recent enough that it continues to hold true for franchise mainstays like Chris Pratt, Bryce Dallas Howard, BD Wong, and more. Though it’s hard to believe, it’s already been nearly a decade since Spielberg’s iconic dino franchise roared back to life with a new cast of characters (and a new director in Colin Trevorrow) as Jurassic World (streaming here on Peacock!) tore through the 2015 summer box office. Remember those wayback days when dinosaurs ruled the Earth? Nope, we’re not even talking about the original 1993 Jurassic Park juggernaut from the spellbinding sci-fi mind of Steven Spielberg. ![]() Garudyne: Deals heavy wind damage to one foe.Mabufudyne: Deals heavy ice damage to all foes on the field. ![]() She can block wind and absorb ice but is weak to fire. Scathach: The ultimate Persona of the Priestess Arcahana. Scatach is a figure in the Ulster Cycle of Irish Mythology and a legendary Scottish Warrior.Fire Amp: Mada's fire attacks are now strengthened by 50%.Ailment Boost: All status ailment attacks are now 1.5 times more effective.Evade Ice: Triples the evasion rate aginst ice attacks.Foolish Whisper: Inflicts mute on enemies.Fire Boost: Mada's fire attacks are boosted by 25%.Agidyne: Deals heavy fire damage to one opponent.Mada: The ultimate Persona of the Magician Arcana.Thunder God Dance: A long combo sequence that ignites Yu's sword with divine lightning.Cross Slash: The sword wielded by Yu charges up with electricity and then slashes his opponent horizantally, followed by Izanagi dropping down and plunging its spear into them.Ziodyne: Deals heavy electric damage to one foe.Raging Lion: Both Yu and Izanaga performs a sliding attack simultaneously.Tarukaja: Increases Yu's attack strength.Rakunda: Decreases the opponent's defense.Zio: Deals weak electric damage to one foe.Resists electricity, blocks darkness, and is weak to wind. A Japanese creation deity born of the seven divine generations. Yu can have his Personas fight for him in battle, by sending them to do attacks, or by using them to cast magic. Persona Summoning: Yu can summon multiple different Personas using his Wild Card ability, each of which besides Izanagi he gained through bonding with another person.True Sight: The ability to see through all illusions and tell truth from lies.Stragetist: Yu is a rational levelheaded genius, and is good at exploiting enemy weaknesses.Detective Skills: Yu's detective skills are almost on par with Naoto's, as he managed to solve the murder mystery in Inaba.He mainly wields two handed swords or blunt weapons, and he's good enough to fight military-grade battle robots and Shadows wielding only his trusty katana. Expert Swordsmen: Yu shows great skills with a sword.Yu was then gifted with the Wild Card, letting him summon multiple Personas depending on the bonds he makes with others. In the alternate world, Yu discovered something known as a Persona, which is what a person's Shadow becomes once they accept it as a part of them, turning it into a warrior that fights for them and grants them new powers. Inside the TV world were the Shadows, monsters formed from the despair and negative emotions of humans. They discovered an alternate world that could be accessed through television screens. Though what they discovered wasn't normal. Yu gets new friends in his new school and decided that with his friends, they will investigate and resolve the urban legend as well as the murderer behind it. Into the small, Countryside town called Inaba, a town that has been experiencing strange murders that are somehow linked to the urban legend of the Midnight Channel. Yu was a transfer student originating from a Big City. ![]() ![]() ![]() Google reserves all rights not expressly granted to you.ģ.4 You may not use the SDK for any purpose not expressly permitted by the License Agreement. "Intellectual Property Rights" means any and all rights under patent law, copyright law, trade secret law, trademark law, and any and all other proprietary rights. You are of course free to develop applications for other platforms, including non-compatible implementations of Android, provided that this SDK is not used for that purpose.ģ.3 You agree that Google or third parties own all legal right, title and interest in and to the SDK, including any Intellectual Property Rights that subsist in the SDK. If you do not have the requisite authority, you may not accept the License Agreement or use the SDK on behalf of your employer or other entity.ģ.1 Subject to the terms of the License Agreement, Google grants you a limited, worldwide, royalty-free, non-assignable, non-exclusive, and non-sublicensable license to use the SDK solely to develop applications for compatible implementations of Android.ģ.2 You may not use this SDK to develop applications for other platforms (including non-compatible implementations of Android) or to develop another SDK. You may not use the SDK if you do not accept the License Agreement.Ģ.2 By clicking to accept and/or using this SDK, you hereby agree to the terms of the License Agreement.Ģ.3 You may not use the SDK and may not accept the License Agreement if you are a person barred from receiving the SDK under the laws of the United States or other countries, including the country in which you are resident or from which you use the SDK.Ģ.4 If you are agreeing to be bound by the License Agreement on behalf of your employer or other entity, you represent and warrant that you have full legal authority to bind your employer or such entity to the License Agreement. The License Agreement forms a legally binding contract between you and Google in relation to your use of the SDK.ġ.2 "Android" means the Android software stack for devices, as made available under the Android Open Source Project, which is located at the following URL:, as updated from time to time.ġ.3 A "compatible implementation" means any Android device that (i) complies with the Android Compatibility Definition document, which can be found at the Android compatibility website () and which may be updated from time to time and (ii) successfully passes the Android Compatibility Test Suite (CTS).ġ.4 "Google" means Google LLC, organized under the laws of the State of Delaware, USA, and operating under the laws of the USA with principal place of business at 1600 Amphitheatre Parkway, Mountain View, CA 94043, USA.Ģ.1 In order to use the SDK, you must first agree to the License Agreement. This is the Android Software Development Kit License Agreementġ.1 The Android Software Development Kit (referred to in the License Agreement as the "SDK" and specifically including the Android system files, packaged APIs, and Google APIs add-ons) is licensed to you subject to the terms of the License Agreement. ![]() ![]() The result is an even more detailed image that makes it possible to see the fetus moving. This produces a 3D image, and the added detail makes it easier to see smaller structures, such as fingers and toes, as well as facial features.Ī 4D ultrasound sends sound waves across multiple planes, with numerous waves per second. In most cases, however, they are accurate - particularly if a skilled doctor analyzes the images and does a follow-up scan.ģD and 4D scans offer greater detail than traditional 2D ultrasound images.Ī 3D ultrasound works by sending sound waves from multiple angles. Ultrasounds cannot detect all pregnancy complications, and they may even suggest issues that are not there. Instead, a doctor will meet with the woman shortly afterward to go over the results. If an ultrasound technician performs the scan, they may not be able to answer questions. the health of the woman and the pregnancy, which may involve looking for signs of problems such as placenta accreta and placenta previa and measuring fluid levels.the fetus’s sex, to see whether the genitals are developing in the usual way.for some congenital disabilities and some early signs of developmental issues.the fetus’s organs, organ systems, and structures, including the brain, skull, heart, face, bones, hands, and feet.the number of fetuses, if this is the first ultrasound of the pregnancy.This may cause pressure, but it should not be painful.Ī 22-week ultrasound to check on the anatomy of the fetus may last about an hour.ĭuring the anatomy scan, the healthcare provider will check: This involves placing a thin transducer into the vagina. They then use a handheld tool called a transducer to generate sound waves, and gently move the tool around the abdomen while checking the relayed images on a monitor.įor the best images, it may help to have a full bladder, which helps the sound waves to travel more effectively.Ī vaginal ultrasound may offer a better image, especially when the fetus is in a certain position. The healthcare provider, possibly a technician, applies gel to the woman’s bare abdomen. Processĭuring an ultrasound, the pregnant woman lies on a table. The most common type is a 2D ultrasound, which offers a simple, somewhat grainy black and white image. The scan is not a photo and cannot capture every detail. An ultrasound scan during pregnancy involves sound waves bouncing off of the fetus and structures in the body to create a rough picture. ![]() ![]() Several chitosan-containing products were approved by the US Food and Drug Administration. Ĭhitosan polymers such as carboxymethyl chitosan (CMC) are suitable for coating nanoparticles by electrostatic interaction and can enhance the physicochemical properties of nanoparticles. Kim and coworkers suggested that loaded AMSN with brimonidine can increase the ocular bioavailability of the drug by increasing the residence time at the preocular surface and controlling the release of the drug. Furthermore, the drug-loaded AMSN could be released in a controlled manner from the particles to maintain a concentration gradient, which improves the drug permeation through the corneal barriers. The hydroxyl groups could form hydrogen bonds with the mucin and the positive charge of the amino groups in the AMSN could also form an ionic complex with the negatively charged groups in mucin. As AMSN has two functional groups, hydroxyl and amine groups, the nanoparticles would be mucoadhesive. (2018) proposed an amino-functionalized mesoporous silica nanoparticle (AMSN) for the ocular delivery of brimonidine for glaucoma. Mucoadhesive materials need to possess a functional group that forms a bond with the mucin. By this approach, many researchers tried nano- or micro-particles made of mucoadhesive polymers such as poly (ethylene glycol), poly (acrylic acid), chitosan, and sodium carboxymethylcellulose for ocular drug delivery. Increasing the residence time of the particles and slowly releasing the loaded drug would improve the ocular bioavailability of the drug. Mucoadhesive particles can be better attached to the mucin on the ocular surface, which increases the residence time in the preocular region. Particles with a mucoadhesive property have been extensively investigated as carriers of ocular drug delivery. Usually, 5-FU eye drops are prepared as an extemporaneous preparation and the solution would be stable for only 7 days. Long-term follow-up is necessary for these patients as the lesions may recur after the therapy. However, the lesion may recur and retreatment is required with an excisional biopsy. The treatment regime for corneal and conjunctival intraepithelial neoplasia, squamous cell carcinoma, and malignant melanoma of conjunctiva can be a pulse ocular doses of 1% 5-FU four times a day for 4 days, for several treatment cycles at monthly intervals. The ocular solution of 5-FU can be used for conjunctival/corneal squamous cell carcinoma. Thus, the 5-FU loaded in AMSN-CMC gel could be used as a topical formulation for the treatment of ocular cancer.ĥ-Fluorouracil (5-FU) is commonly used to treat many cancer diseases including epithelial cancers. AMSN-CMC-FU gel and AMSN-FU gel were “minimally irritating” to rabbit eyes but showed minimal eye irritation potency in comparison to the 5 FU gel. AMSN-CMC-FU showed 1.52- and 6.14-fold higher AUC0-inf in comparison to AMSN-FU and 5-FU gel, respectively. Higher bioavailability of AMSN-FU and AMSN-CMC-FU gel formulations was found compared to 5-FU gel in the ocular pharmacokinetic study with superior pharmacokinetics parameters of AMSN-CMC-FU gel. AMSN-CMC-FU initially exhibited a 2.45-fold increase in transcorneal flux and apparent permeation of 5-FU compared to 5-FU gel, indicating a better corneal permeation. Release profiles showed 100% of the drug was released from the 5-FU gel within 4 h, while AMSN-FU gel released 20.8% of the drug and AMSN-CMC-FU gel released around 55.6% after 4 h. In addition, TGA, FTIR, and PXRD confirmed the drug loading inside the AMSN-CMC. NMR spectra confirmed the coating of AMSN with the CMC layer. The optimum formulation of AMSN-CMC-FU was found to be nanoparticles with a particle size of 249.4 nm with a polydispersity of 0.429, encapsulation efficiency of 25.8 ± 5.8%, and drug loading capacity of 5.2 ± 1.2%. Eye irritation and ocular pharmacokinetic studies from gel formulations were evaluated in rabbit eyes. The transcorneal permeabilities of 5-FU from AMNS-FU and AMSN-CMC-FU gel formulations were estimated through excised goat cornea and compared to that of 5-FU gel formulation. The mucoadhesion ability of the prepared nanoparticles was tested using the particle method by evaluating the change in zeta potential. In vitro release was conducted through a dialysis membrane in PBS (pH 7.4) using modified Vertical Franz diffusion cells. ![]() Physicochemical characterizations were performed by NMR, TGA, FTIR, and PXRD. The drug encapsulation and loading were determined by the indirect method using HPLC. Particle characterization was performed by the DLS technique (Zeta-Sizer), and structural morphology was examined by SEM and TEM. This study investigates the development of topically applied non-invasive amino-functionalized silica nanoparticles (AMSN) and O-Carboxymethyl chitosan-coated AMSN (AMSN-CMC) for ocular delivery of 5-Fluorouracil (5-FU). ![]() These opinions, findings, or experiences may not be representative of what all customers may achieve. Certain restrictions and limitations may apply.ġ0 The Testimonials on this page or provided via linked videos are the sole opinions, findings or experiences of our customer and not those of JPMorgan Chase Bank, N.A. See the Deposit Account Agreement for details.ĩ Chase Online Bill Pay: Must enroll in Chase Online SM Banking and activate Online Bill Pay. ![]() Zelle and the Zelle related marks are wholly owned by Early Warning Services, LLC and are used herein under license.Ĩ You may be charged fees for using non-Chase ATMs by both Chase and the ATM owner/network. Neither Chase nor Zelle ® offers a protection program for any authorized payments made with Zelle ®, or provide coverage for non-received, damaged, or not-as-described goods and services you purchase using Zelle ®, so you might not be able to get your money back once you send it. Only send money to people and businesses you trust. ![]() Enroll on the Chase Mobile ® app or Chase Online SM. Select transactions could take up to 3 business days. mobile number is already enrolled with Zelle ® (go to to view participating banks). Funds are typically made available in minutes when the recipient's email address or U.S. To send money to or receive money from a small business, both parties must be enrolled with Zelle ® directly through their financial institution's online or mobile app experience. Chase customers must use an eligible Chase consumer or business checking account, which may have its own account fees. checking or savings account is required to use the service. Your savings may vary.ħ Enrollment in Zelle ® with a U.S. Message and data rates may apply.Ħ Savings represents the average monthly reported savings on fees for money orders, check cashing, US remittances, and bill paying services by 1064 Chase Secure Banking customers who responded to a Chase survey fielded in July 2022. Even if you have a negative balance, we will not charge you an overdraft fee.ĥ Chase Mobile ® app is available for select mobile devices. However, you could still end up with a negative balance if, for example, a transaction is approved for one amount, but then the actual charge is more than what you have in your account (like when you add a tip at a restaurant after the transaction for the meal was already approved). After that the Monthly Service Fee will apply unless you meet one of the ways to avoid the Monthly Service Fee each statement period (if applicable).Ĥ We will decline or return transactions when you do not have enough money in your account to cover the charge. See /disclosures for more information.ģ New and converted accounts will not be charged a Monthly Service Fee for at least the first two statement periods. Eligible transactions are certain ACH credit transactions such as payroll, government benefits or similar transactions.Ģ There is a $4.95 Monthly Service Fee. This means when these transactions are credited could vary and you may not receive your funds early. The timing of when these transactions will be credited is based on when the payer submits the information to us. You must set up direct deposit to your account. Nomber_key:0000401 For Chase Secure Checking SM only: Early direct deposit is a service that comes with your Chase Secure Checking account in which we credit your eligible direct deposit transaction up to two business days early. Even better, as you play and unlock accessories and decorations, you can customize your character's appearance even more with various hairstyles, shoes, makeup, and tattoos. Thanks to this powerful editor, you can create whatever look you want. There are hundreds of different options for creating literally thousands of different combinations. When you sign up for IMVU, the first thing you do is create your avatar. In a way, it's like a mix between Second Life and instant messaging. Present, include filters, and post images to get people talking.IMVU is a hybrid between a social network and a persistent world game, where you can create and customize your own avatar and explore an expansive open world filled with thousands of other players from all over. 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